Opening Odds for Bills vs. Chiefs in the 2025 NFL Playoffs: AFC Championship Game Preview

The Kansas City Chiefs will host the Buffalo Bills on Sunday, January 26 with kickoff set for 6:30 p.m. ET. The Chiefs opened as a 1.5-point favorite at FanDuel Sportsbook in hypothetical lines ahead of the Bills/Ravens Divisional Round win.

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Alade-Ọrọ̀ Crow

Kansas City Chiefs v Buffalo Bills

Get ready for an exciting showdown as we preview the opening betting lines for the highly anticipated AFC Championship Game featuring the Buffalo Bills and the Kansas City Chiefs in the 2025 NFL playoffs.

Mark your calendars for Sunday, January 26, when the Kansas City Chiefs will host the Buffalo Bills at 6:30 p.m. ET. The Chiefs have opened as a 1.5-point favorite at FanDuel Sportsbook, following the Bills’ victory over the Ravens in the Divisional Round. The total for this matchup has opened at -110.

The Chiefs are making their seventh consecutive AFC Championship appearance after defeating the fourth-seeded Texans 23-14 in the Divisional Round. Under the leadership of star quarterback Patrick Mahomes, Kansas City has reached the conference championship game every season he has started. Remarkably, they have made it to the Super Bowl four times, clinching three titles. As they aim for a historic three-peat, the Chiefs look to solidify their legacy in NFL history.

This matchup marks the fourth postseason encounter between the Bills and the Chiefs since 2020, adding to the excitement of this fierce rivalry.

Buffalo Bills vs. Kansas City Chiefs

Opening point spread: -1.5
Opening point total: 47.5
Opening moneyline: Bills -107, Chiefs -110

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